Andrea B. Fourcaudot

United States Army Institute of Surgical Research

Andrea B. Fourcaudot's research focuses on understanding the complexities of wound healing and bacterial infections in burns, with a emphasis on the pathogenicity of Pseudomonas aeruginosa. By comparative transcriptome analysis of burn wounds in different pig models, their work highlights the differences in response to infection between superficial and deep partial-thickness burns. The findings also demonstrate how T3SS and alginate biosynthesis contribute to Pseudomonas aeruginosa's ability to impair wound healing, while cerium nitrate treatment shows promise in stabilizing eschar by reducing bioburden and inflammation. These studies have significant implications for burn care and wound management, particularly in relation to bacterial infections and scarring.