59.8
Anne-Sofie Grell
Rigshospitalet, Glostrup Hospital, Copenhagen University Hospital
Researchers Anne-Sofie Grell and colleagues have made significant contributions to our understanding of cerebrovascular biology and disease. Through studies on subarachnoid haemorrhage, hypertension, and cerebral ischemia, their work has shed light on key molecular mechanisms governing blood vessel function and response to injury. The development of fluorescent analogues for α-calcitonin gene-related peptide and fremanezumab, a potential therapeutic agent targeting cGRP-induced vasodilation, holds promise for treating conditions characterized by severe vasoconstriction. Furthermore, research on oxytocin's regulatory role in the trigeminovascular system and its receptors has implications for understanding late cerebral ischemia after subarachnoid hemorrhage.