65.1
Christopher L. Douglas
University of Oxford
Christopher L. Douglas has made significant contributions to various fields, including pharmacology, algebraic topology, and neuroscience. Research on high-dose methotrexate in pediatric patients with acute lymphoblastic leukemia and sacubitril-valsartan, a new heart failure medication, has improved understanding of population pharmacokinetics and treatment outcomes. In algebraic topology, studies on conformal nets and fusion rings have shed light on cornered Floer homology and the Segal conjecture for tori. Additionally, research on sleep and breathing in rodents has elucidated the role of cholinergic modulation, with findings highlighting potential therapeutic targets for sleep disorders and respiratory conditions.