65.0
Donatella Montanaro
Ceinge Biotecnologie Avanzate (Italy)
Donatella Montanaro's research has significantly advanced understanding in various fields, including cancer biology, immunology, and cell signaling. Studies have identified key genetic drivers of breast cancer, such as the akt1e17k allele, which promotes tumor growth in mice. Additionally, research on long intergenic non-coding RNAs revealed distinct biomarkers for differentiating between luminal and triple-negative breast cancers. In cardiovascular disease, helper-dependent adenovirus-mediated gene transfer has shown promise in reducing atherosclerosis in mice. Furthermore, investigations into metastatic brain tumors and neuroblastoma have uncovered critical regulatory pathways, including the role of CD55 and Prune1.