71.9
H. Franklin Bunn
Brigham and Women's Hospital, Harvard University
H. Franklin Bunn's research has significantly advanced our understanding of oxygen delivery and hemoglobin-related disorders. Contributions to the treatment of anemia, sickle cell disease, and other conditions highlight the critical role of increasing oxygen affinity of hemoglobin, targeting hbs polymerization, and identifying novel reductases such as ncb5or. The study of red blood cell size distribution variation and classification of hemoglobin disorders has provided valuable insights into the complexities of these diseases. Moreover, research on pulmonary hypertension, nitric oxide depletion, and hypoxia-inducible factor (HIF) activity has shed light on cellular mechanisms underlying these conditions. These findings have far-reaching implications for the diagnosis, treatment, and prevention of various diseases.
Firms applying this knowledge
Beam Therapeutics Inc., The University Of Adelaide, University Of Utah Research Foundation, The Kenneth S. Warren Institute, Inc.