58.5
Kentaro Misaki
Ehime University, University of Shizuoka
Kentaro Misaki's research has significantly advanced the understanding of polycyclic aromatic hydrocarbons (PAHs) and their environmental and health implications. Studies have evaluated PAHs' antiandrogenic, estrogenic, and biological response-enhancing activities, as well as their potential to inhibit algal photosynthesis and induce DNA damage in natural organic matter. Additionally, research has identified tumour-promoting activities of PAHs and their oxygenated or nitrated derivatives, highlighting the importance of aryl hydrocarbon receptor (AhR) mediation in these processes. Furthermore, work on AhR ligand activity of polycyclic aromatic ketones and quinones has shed light on potential mechanisms underlying PAH toxicity, ultimately contributing to human risk assessment and informing strategies for mitigating exposure to PAHs in urban environments.