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Laetitia Moeckes
Laboratoire de Génétique Cellulaire
Laetitia Moeckes has made significant contributions to the field of regenerative medicine with their work on generating transgene-free hematopoietic stem cells (HSCs) from human induced pluripotent stem cells (iPSCs). This breakthrough research addresses a major bottleneck in the use of iPSCs for personalized therapies, such as bone marrow transplantation and immunotherapy. By developing a reliable method to generate HSCs without viral vectors or transgenes, Moeckes' work opens up new avenues for safe and efficient hematopoietic reconstitution. The implications are far-reaching, enabling potential treatments for blood disorders and cancer, and advancing the field of iPSC-based therapies.