58.8
Lila Rieber
Pennsylvania State University
Lila Rieber's research has significantly advanced our understanding of mammalian Hox cluster regulation through the development of synthetic regulatory reconstitution methods. By applying these approaches to genome structure alignment and chromatin interaction analysis, Rieber's work reveals novel insights into compartment-independent reorganization across cell types and characterizes yeast protein-genome interactions in response to heat shock. These findings have broad implications for understanding developmental biology, gene regulation, and cellular responses to environmental stressors. The research also highlights the potential of synthetic genomic reconstitution as a tool for elucidating regulatory mechanisms at the genome-wide level, driving future investigations into human disease models.