65.7
Mahesh S. Joshi
University of Miami
Mahesh S. Joshi has made significant contributions to understanding cognitive resilience in brain health and dementia research, as well as the mechanisms underlying nitric oxide (NO) production and signaling pathways in various tissues. Research findings have highlighted the importance of NO-dependent relaxation mechanisms in vascular smooth muscle cells, with implications for hypertension, salt-sensitive cardiovascular disease, and renal function. Additionally, Joshi's work has elucidated the role of agmatine, a biogenic amine, in mediating NO production and its impairment in certain pathological conditions, such as hypertension and kidney injury. These studies have important relevance for developing novel therapeutic strategies targeting NO signaling pathways.
Firms applying this knowledge
The Florida International University Board Of Trustees, University Of Delaware, The University Of Massachusetts, Loma Linda University, The United States Of America As Represented By The Secretary, Department Of Health And Human Services