Melanie Gonsior

Technische Universität Berlin

Melanie Gonsior's research has significantly advanced our understanding of glycopeptide antibiotic biosynthesis. By elucidating the complex interactions between cytochrome P450s and non-ribosomal peptide synthetases, Gonsior's work has shed light on the molecular mechanisms underlying this critical process in bacteria. The study also uncovered a novel linear non-ribosomal peptide synthetase mechanism responsible for the production of the peptide antibiotic feglymycin. This research holds substantial implications for the development of new antibiotics and antimicrobial therapies, as well as our understanding of bacterial metabolism and biosynthetic pathways. Gonsior's findings have the potential to inform strategies for combating antibiotic resistance.