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William H. van der Schalie
Walter Reed Army Institute of Research, General Dynamics (United States)
William H. van der Schalie's research contributes significantly to the fields of environmental science and toxicology, focusing on the development of innovative methods for assessing waterborne contaminants. Through high-throughput embryonic zebrafish tests and a multistep enrichment process, their work improves the understanding of nanomaterial toxicity and resuscitation of chlorine-stressed bacteria from secondary sewage effluents. Additionally, they investigate photomotor response sensitivity in zebrafish embryos exposed to neurotoxic chemicals and develop portable cell-based impedance sensors for rapid toxicity testing of drinking water. These advancements enhance the U.S. Environmental Protection Agency's alternate test procedure protocol and provide insights into ecological risk assessment, highlighting the importance of harnessing advanced technologies for real-time toxicity detection and water quality monitoring.